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Setauket is a village located in Suffolk County in the Town of Brookhaven, on the North Shore of Long Island, New York. As part of Brookhaven's Three Village area, Setauket varies considerably as one travels north to south. In Setauket's Old Field there are wealthy waterfront estates on Long Island Sound many from earlier decades. Among them is the New England style village green with a mill pond and park, a quaint post office, and the Caroline Church which was built in 1729. In 1655, the area was first settled by six pioneers who bought land from the Setalcott Indians. The name "Setauket" comes from the Setalcott Indians, who had previously lived in the area. No townsman was permitted to sell land to an outsider and no one could move into the settlement with a favorable vote from those already living there. The former and merged names of Setauket include Ashford. During the American Revolutionary War, the Culper Spy Ring headed by Benjamin Tallmadge passed information about British troop movements gathered in New York City to George Washington. The Battle of Setauket was fought here in 1777. Setauket has also a record of active governance in the affairs of Brookhaven and was its capital for a long time. It was considered as a shipbuilding town in the 19th-century.

There are two historic churches: Caroline Church (built 1730) and Setauket Presbyterian Church (originally built 1674), both built on Setauket Greens area. Up the road near these churches is the Greek Orthodox Monastery of the Holy Cross. Other attractions include the Village Green, the Emma S. Clark Memorial Library, Three Village Garden Club Arboretum and Nature Preserve, historic Setauket Post Office, Setauket Neighborhood House and the Setauket Mill Pond. The Thompson House (91 North Country Road at Old Town Road) is another registered historic place in Setauket. The Long Island Museum features one of the largest collection of horse-drawn carriages in the world, as well as paintings by William Sydney Mount. It is also the host of an annual folk festival.

North Shore Eye Care serves the residents of Setauket with a variety of concerns including Macula Degeneration. New treatments offer better hope for people with macula degeneration. Macula degeneration is a leading cause of visual loss and even blindness. Luckily, it usually presents later in life and commonly is a result of blood vessel disease, which may occur as a result of diabetes, hypercholesteremia, and hypertension. Diabetes which can affect vessels in many parts of the body often affects the very smallest vessels in the eye known as capillaries. Hypercholesteremia and hypertension result in arteriosclerosis which usually affects the veins, but also the arteries when there is ocular invovement. "Wet type macula degeneration" is a specific disease affecting the eye only and involves abnormal vessel formation.

In the last few years new treatment modalities have become available to treat the above problems with remarkable results. These may involve use of corticosteroids which can be safely injected into the eye yielding much higher concentrations than if taken orally or intravenously. A new novel way of doing this is to inject a bioerodable implant into the eye known as ozurdex. Other chemicals known as vascular endothelial growth factor inhibitors can also produce dramatic results. In many cases older treatments involving laser therapy can still be useful.